Now the same scientists…

...at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health, have also identified a unique pattern of immune molecules in the cerebrospinal fluid of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) that provides insights into the basis for cognitive dysfunction – frequently described by patients as "brain fog" – as well as new hope for improvements in diagnosis and treatment.

Scientists find clues into cognitive dysfunction in chronic fatigue syndrome

EurekAlert! 

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A second study,…

… published Monday by the Proceedings of the National Academy of Sciences, confirm the presence of XMRV and other MRV-related viruses in a high proportion of chronic fatigue syndrome patients. Scientists found gene sequences from several MRV-related viruses in blood cells from 32 out of 37 chronic-fatigue patients but only 3 of 44 healthy ones.

Chronic Fatigue Linked to Virus Class
New York Times - 23 August 2010
When the journal Science published an attention-grabbing study last fall linking chronic fatigue syndrome to a recently discovered retrovirus, many experts remained skeptical — especially after four other studies found no such association.

Reference:

Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
Shyh-Ching Lo, Natalia Pripuzova, Bingjie Li, Anthony L. Komaroff, Guo-Chiuan Hung, Richard Wang, and Harvey J. Alter
PNAS published ahead of print August 23, 2010, doi:10.1073/pnas.1006901107


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Could these drugs...

... be something that would work for CFS?

Researchers Identify Drugs that Enhance Exercise Endurance HHMI News - July 31, 2008

... Researchers have identified two drugs that mimic many of the physiological effects of exercise. The drugs increase the ability of cells to burn fat and are the first compounds that have been shown to enhance exercise endurance.

Both drugs can be given orally and work by genetically reprogramming muscle fibers so they use energy better and contract repeatedly without fatigue. In laboratory experiments, mice taking the drugs ran faster and longer than normal mice on treadmill tests. Animals that were given AICAR, one of the two drugs, ran 44 percent longer than untreated animals. The second compound, GW1516, had a more dramatic impact on endurance, but only when combined with exercise.

Ronald M. Evans, the Howard Hughes Medical Institute investigator who led the study, said drugs that mimic exercise could offer potent protection against obesity and related metabolic disorders. They could also help counter the effects of devastating muscle-wasting diseases like muscular dystrophy. Evans and his colleagues, who are at the Salk Institute for Biological Studies, published their findings on July 31, 2008, in an advance online publication in the journal Cell. ...

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Seven different genetic types of CFS’ discovered...

Geneticists from St George's Hospital, University of London have identified a biological basis for seven different subtypes of chronic fatigue syndrome.

The research findings are to be presented to a conference in Cambridge.

Read more: Seven genetic types of ME' found

BBC - Monday, 5 May 2008 00:02 UK

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