Tuesday 12 February 2008

I wonder if...

...this has anything to do with the extreme fatigue in CFS also!

ZenMaster

Fatigue relief drug's heart hope

BBC News, UK - Feb. 11, 2008

Scientists are developing a drug which relieves fatigue after strenuous exercise - and it could benefit heart failure patients as well.

Leaky Muscle Cells Lead To Fatigue

Science Daily - Feb. 11, 2008

What do marathoners and heart failure patients have in common? More than you think according to new findings by physiologists at Columbia University Medical Center.

Finding May Solve Riddle of Fatigue in Muscles

New York Times, United States - Feb. 11, 2008

One of the great unanswered questions in physiology is why muscles get tired. The experience is universal, common to creatures that have muscles, but the answer has been elusive until now.

References

Remodeling of ryanodine receptor complex causes "leaky" channels: A molecular mechanism for decreased exercise capacity

Bellinger, A. M. et al. Proc. Natl Acad. Sci. USA 105, 2198-2202 (2008).